Microarray and Next Generation DNA sequencing technologies have given us new abilities to understand how living things respond to environmental change. One of the ways we can use this new information is to study gene expression under different conditions. In this activity, we will explore microarray data from plants as they experience drought. Read more
For many years, I've been perfectly content to work with small numbers of things. Working with one gene or one protein is great. Even small groups of genes are okay. I'm fine with alternatively spliced genes with multiple transcripts, or multiple polymorphisms, or genes in multi-gene families, or groups of genes in operons.
But I never trusted microarrays.
First, there were all the articles questioning the ability to reproduce microarray data. For many years, people reported difficulties in reproducing experiments, especially if they used chips from different ... Read more